Thursday, 21 February 2019

Interesting facts about Vanillin




Image result for vanillin controversyImage result for vanillin controversy


I bet a lot of you have consumed at least one thing that has vanilla as its flavouring. Vanilla ice-cream, cake, vanilla syrup in your ice coffee, French vanilla latte, vanilla flavoured lotions, etc. It is such a common flavour used excessively in a lot of industries. Personally, I used to think it was only used in food products, but after some research on the compound 'Vanillin' (the chemical comprising vanilla) I learnt that it can be more than a flavouring compound. It is a source of L-dopa, which is a very important drug used in the treatment of Parkinson's disease (4). It can also be used as a starting material for production of methyldopa, another important drug that is commonly used to lower blood pressure (7). It is also widely used as a preservative and has shown to increase shelf life upto 60 days (3). Furthermore, it has some industrial uses and used in insecticides to attract insects due to its sweet smell.

Its consumption in humans is safe (the most dangerous effect being eye irritations), hence it is still being used in production of food products, cosmetics and drugs (5). Some people can be allergic to Vanillin (1). Some studies showed that small doses of vanillin can be lethal in mouse and rats if inhaled (6).

Despite its many uses, the availability of organic vanilla is scarce: vanilla bean or ferulic acid in rice and oats. Although there are many other sources that can be used to produce artificial vanilla. These are available from cloves in the form of eugenol oil, ylang ylang plant (tropical plant) that produces isoeugenol, and turmeric with curcumin extracts (2). These extracts can undergo chemical processes to give synthetic vanillin and hence, synthetic vanilla extracts (2). You must have noticed that all these extracts whether organic or inorganic come from plants. Thus, a huge controversy surrounding vanillin is in regards to "What's 'natural' and what's 'artificial'".

References: 
1. Bingham, E., Cohrssen, B., & Powell, C.H. (2001). Patty's Toxicology (5th ed.). New York, NY: John Wiley & Sons.



2. Burdock, G.A. (2001). Fenaroli's Handbook of Flavor Ingredients (6th ed.). Boca Raton, FL

3. Cerrutti P et al. (1997). J of Food Science, 62(3), 608-610.

4. Lewis, R.J. Sr. (2007). Hawley's Condensed Chemical Dictionary (15th ed.). Inc. New York, NY: John Wiley & Sons.

5. Lewis, R.J. (1996). Sax's Dangerous Properties of Industrial Materials (9th ed.). New York, NY: Van Nostrand Reinhold

6. Tamai K et al. (1992). Mutat Res, 268(2), 231-7.

7. Vidal J.P. (2006) Vanillin. Kirk-Othmer Encyclopedia of Chemical Technology (1999-2015). John Wiley & Sons, Inc.








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